REDUCTION IN CARDIOLIPIN REDUCES EXPRESSION OF CREATINE TRANSPORTER-1 AND CREATINE TRANSPORT IN GROWING HCMEC/D3 HUMAN BRAIN MICROVESSEL ENDOTHELIAL CELLS

15-eg1053cl The phospholipid cardiolipin (CL) regulates mitochondrial energy production.Endothelial cells of the blood-brain barrier (BBB) play a vital role in uptake of metabolites into the brain and are enriched in mitochondria.We examined how deficiency in BBB endothelial cell CL regulates the expression of selected drug and metabolite transport

The most important dogma in white-wine production is the preservation of the wine aroma and the limitation of the oxidative action of oxygen.In contrast, the ageing of Sherry and Sherry-like wines is an aerobic process that depends on the oxidative activity of flor strains of Saccharomyces cerevisiae.Under depletion of nitrogen and fermentable carb

Background: Among chemical beetroot birkenstock dyes, Azo dyes, as environmental synthetic pollutants, are most commonly used in a bunch of different colors in different industries, especially in textile industry to a large extent.Methods: Due to some limitation and difficulties to remove these pollutants from the environment, the biological filter

This research aimed at analysing the economic feasibility of stablishing agroforestry system with eucalypt in savanna areas.The wood produced should be allocated to sawmills and energy production.The effect of changes in the discount rate, land value, prices of wood, soybean and rice, the proportion of wood destined to sawmill and energy and produc

Bone cancer is treated as a severe health problem, and, in many cases, it causes patient death.Early detection of bone cancer is efficient in reducing the spread of malignant cells and decreasing mortality.Since the manual detection process is a laborious task, it is needed to design an automated system to classify and identify the cancerous bone a